Peripheral nerves in early experimental diabetes

The regenerative deficit of peripheral nerves in experimental diabetes: its extent, timing and possible mechanisms.

Diabetes mellitus is reported to impair peripheral nerve regeneration, but the extent, timing and selectivity of the deficit is unclear. We studied regeneration of motor and sensory fibres in mice with experimental diabetes induced using streptozotocin (STZ). The mouse model featured several advantages over its counterpart in rats given STZ, while exhibiting the expected slowing of motor conduc...

Therapeutic Potential of Dioscorea Extract (DA-9801) in Comparison with Alpha Lipoic Acid on the Peripheral Nerves in Experimental Diabetes

DA-9801, a mixture of extracts from Dioscorea japonica Thunb. and Dioscorea nipponica Makino, was reported to have neurotrophic activity. Therefore, we investigated the therapeutic potential of DA-9801, in comparison with alpha lipoic acid (ALA), for peripheral nerves preservation in experimental diabetes. Experimental animals were divided into 4 groups, and each group was designated according ...

Injuries to Peripheral Nerves

the proximal to the distal segment. These cells may be formed by the breaking up of the myelon sheath, and it is asserted by some of the exponents of centrifugal regeneration that it is by means of these newly-organized myelon fragments that a chemical attraction is created which enables the new axons to find their way into the partly obliterated distal cord. All this doubt and speculation make...

Introduction of a New Suture Method in Repair of Peripheral Nerves Injured with a Sharp Mechanism

  Background: The standard method for repair of an injured peripheal nerve is epineural repair with separate sutures. Herein we describe a method in which the nerve is sutured with continous sutures. In fact this method has not been utilized for nerve repair previously and our purpose was to compare it to the standard method. If it proved to be successful it would replace the standard method in...

War Injuries of Peripheral Nerves.